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In a recent phase 3 trial with patients with T2D and inadequate glycaemic control, the mean percentage change from baseline body weight with the 12-mg dose of retatrutide at 40 weeks was -15.3% [19]

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When administered at doses of 0, 0.1, 0.25, and 0.5 ug/mL, growth hormone receptor expression was increased in a dose-dependent manner