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Kawas resigned from Athira in 2021, and in January 2025 Athira agreed to pay $4,068,698 to settle False Claims Act allegations that it failed to report those research-misconduct allegations to NIH and the HHS Office of Research Integrity in grant applications, progress reports and assurances covering research that referenced the papers — including the $15.2 million Alzheimer's grant awarded in December 2020

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Important Caveats About the Research Several important limitations should be acknowledged when reviewing the EpitalON literature: The majority of published studies originate from Khavinson's research group or closely affiliated laboratories Independent replication outside Russia has been limited, though the 2025 Biogerontology study represents a notable exception Human clinical data remains sparse, consisting mainly of small studies from one research group Most research has used injectable EpitalON, not oral formulations The peptide is not approved as a medicine in the UK, EU, or US How EpitalON Capsules Are Typically Taken Research Protocol Context The research literature commonly references cycles of 10-20 days at 5-10mg daily, repeated periodically (such as once or twice yearly)