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The cell-culture environment in published work uses GH supplementation that may not reflect baseline physiological conditions

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Lipopolysaccharide (LPS) on the outer membrane of Gram-negatives are a common PAMP known to induce inflammatory responses (e.g., IL-8) and subsequently inducing mucin secretion (e.g., MUC5AC, MUC5B) (Smirnova et al., 2003