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It is then translocated to the cell nucleus where it interacts with the retinoid X receptor and nuclear receptor 77 to form a complex that can regulate transcription and can induce apoptosis (12, 13) (Fig

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1 H NMR (D 2 O): δ (ppm) (Figure S24B): 8.51 (s, 1H, e), 7.21 (s, 1H, e′), 4.65 (m, 1H, c), 4.50 (dd, 1H, r′), 4.28–4.35 (m, 2H, r+f),3.74 (dd, 2H, b), 3.25 (m, 1H, q), 3.17 (dd, J1 15.3 Hz, J2 6.5 Hz, 1H, d), 3.09 (dd, J1 15.4 Hz, J2 7.4 Hz, 1H, d′), 2.897–2.93 (m, 3H, s,l), 2.67 (m, 1H, s′), 2.26 (t, J 7.2 Hz, 2H, m), 1.46–1.81 (m, 10H, g,i,o,p,n), 1.35 (m, 2H, h)