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If you suffer from mild depression once in a while, you can try a B12 shot as a mood booster – some people have reported feeling happily giddy afterwards, but not for long

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Choline can be supplied from diet, or made in the body as phosphatidyl choline via the PEMT enzyme There can be SNPS in PEMT, reducing activity, or it may be depleted by reduced methylation as it is SAMe-dependent