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NNMT (nicotinamide N-methyltransferase) catalyses the methylation of nicotinamide using S-adenosylmethionine (SAM) as the methyl donor, producing 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine

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Mechanism of Nasal Drug Delivery to Brain The exact mechanisms of IN drug delivery to the CNS are not completely understood [6,8]