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ACE-inhibitory peptides potentially block the active site of ACE and diminish the conversion of angiotensin I to angiotensin II, thus alleviating blood pressure [117]

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Consistent with these gene expression and proteome changes, mouse brain metabolome analysis found that the ratio of C12-C18 long chain acylcarnitines to C6-C12 medium chain acylcarnitines increased with aging, suggestive of decreased long-chain fatty acid beta-oxidation in the aged brain (Borkowski et al., 2025)