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313 Twinkle, encoded by C10orf2 , is essential for nascent H-strand synthesis in the D-loop and is thus indispensable for mtDNA replication, despite the existence of other potential mtDNA helicases

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After tumor spheroids were visible in culture, brightfield microscopy images (× 20 magnification) were obtained using Cytation 5 Cell Imaging Multi-Mode Reader (BioTek, VT)

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