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Histology results Before the initiation of therapy, at 10 min after injury induction, a large hemorrhagic zone was present over the lateral and posterior white columns in all of the rats, but there were no changes in the gray matter

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Such behavioral deficits in A53T mice were accompanied by the presence of elevated α-synuclein monomers and aggregates (Supplemental Figure 1J) and a remarkable loss of dopaminergic neurons in the substantia nigra, as indicated by tyrosine hydroxylase (TH) staining (Figure 1C)