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CA showed significantly higher thrombolysis in cerebral infarction (TICI) 2b/3 scores at the end of the procedure (OR = 1.99, 95% CI [1.04, 3.81]), higher favorable modified Rankin Scale (mRS) at 3 months (OR = 1.28, 95% CI [1.03, 1.58]), and fewer adverse events (OR = 0.70, 95% CI [0.50, 0.98]) compared to combined treatment

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Because parenteral MeCbl preparations must also meet stringent sterility and endotoxin limits, these characteristics have direct implications for formulation development, compounding, and storage: Light Sensitivity MeCbl readily undergoes photodegradation when exposed to ambient or ultraviolet light, leading to loss of potency and formation of breakdown products