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Oral Protocol Essentials Standard dose: 500–1,000 mcg, 1–2× daily Empty stomach for systemic effects: 30–60 minutes before meals or 2 hours after With food for gut-coating effects: take alongside meals Storage: capsules should be refrigerated

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A notable pharmacological interaction exists with ACE inhibitors, as the Tβ4 metabolite Ac-SDKP is normally degraded by ACE