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The antioxidant capacity of silymarin can lower oxidative stress (in the liver) associated with acetaminophen metabolism in rats, which has the effect of conserving cellular glutathione levels (Campos 1989)

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Isorhamnetin also inhibits angiogenesis and metastasis by downregulating VEGF and MMP-2/9 expression in breast, liver, and lung cancers [95,280]